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  7. BAY-u 3405, Tocris Bioscience™

BAY-u 3405, Tocris Bioscience™

Catalog No. p-4783778 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Dual TP/DP2 (CRTH2) receptor antagonist

Potent dual antagonist of TP/DP2 (CRTH2) prostanoid receptors (Ki values are 4.3, 4.5 and > 10000 nM for hDP2, hTP and hDP1 receptors respectively). Suppresses PGD2-induced migration of human eosinophils (IC50 = 170 nM).

Chemical Identifiers

CAS 116649-85-5
Molecular Formula C21H21FN2O4S
Molecular Weight (g/mol) 416.467
InChI Key LDXDSHIEDAPSSA-OAHLLOKOSA-N
Synonym ramatroban, baynas, unii-p1ali72u6c, 3h ramatroban, 3h baynas, baynas tn, ramatroban jan/inn, p1ali72u6c, 3-4-fluorophenylsulfonamido-1,2,3,4-tetrahydro-9-carbazole propanoic acid, +-3r-3-p-fluorobenzenesulfonamido-1,2,3,4-tetrahydrocarbazole-9-propionic acid
PubChem CID 123879
IUPAC Name 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid
SMILES C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O

Specifications

Quantity 10 mg
Formula Weight 416.47
Percent Purity >99%
Chemical Name or Material BAY-u 3405

Safety and Handling

Recommended Storage Desiccate at -20°C
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