BD Annexin V: FITC Fluorescence Microscopy Kit

Includes

Annexin V-FITC, Annexin V Binding Buffer, and PBS Buffer

Fluorescence staining for apoptosis

Early in apoptosis, before the loss of membrane integrity,phosphatidylserine (PS) translocates from the inner to outer leaflet of plasma membrane, exposing it to external cellular environment at surface of plasma membrane. Annexin V is 35-36kDa, calcium-dependent, phospholipid-binding protein with a high affinity for PS and is used to indirectly monitor PS translocation. Annexin V assay is facilitated by the observation that PS translocation appears to be a universal apoptotic phenomenon.

• Binds to negatively charged phospholipid surfaces
• Defined calcium and salt concentrations are required

Used in Fluorescence microscopy

For Use With (Application)

Fluorescence Microscopy

Includes

Annexin V-FITC, Annexin V binding buffer, and PBS buffer

Quantity

25 Slides

Content And Storage

4°C

Product Type

Fluorescence Microscopy Kit

Research use only