Learn More
beta-Estradiol, 99% (dry wt.), ca 3% water, Thermo Scientific Chemicals
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner′s syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.
Solubility
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Notes
Incompatible with strong oxidizing agents.
Specifications
Melting Point
175°C to 178°C
Quantity
5 g
Beilstein
1914275
Merck Index
14,3703
Solubility Information
Soluble in dimethyl sulfoxide,ethanol ,water,phosphate buffer saline,dimethyl formamide,acetone,dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Optical Rotation
+79° (c=1 in Dioxane)
Formula Weight
272.39
Percent Purity
99%
Assay
(dry wt.), ≈3% water
Chemical Name or Material
beta-Estradiol
Hazard Category
H350-H361fd-H362-H373
Hazard Statement
GHS H Statement
H350-H360
May cause cancer.
May damage fertility or the unborn child.
Precautionary Statement
P201-P202-P260-P263-P264b-P270-P271-P281-P304+P340-P308+P313-P501c
EINECSNumber
200-023-8
RTECSNumber
KG2975000
TSCA
No
Recommended Storage
Ambient temperatures
RUO – Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.