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Bexarotene, 98%, Thermo Scientific Chemicals
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.
Solubility
Soluble in DMSO and ethanol
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Specifications
Melting Point
220°C to 225°C
Color
White
Quantity
100 mg
Merck Index
14,1194
Solubility Information
Soluble in DMSO and ethanol
Formula Weight
348.48
Percent Purity
≥99%
Physical Form
Powder
Chemical Name or Material
Bexarotene
Hazard Category
H302-H315-H319-H335
Hazard Statement
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
RTECSNumber
DH6834830
TSCA
No
Recommended Storage
Store at -20°C
RUO – Research Use Only
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