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BINA, Tocris Bioscience™

Catalog No. p-4816930 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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Description

Selective positive allosteric modulator of mGlu2

Selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). Displays no effect on glutamate-induced activation of other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.

Chemical Identifiers

CAS 866823-73-6
Molecular Formula C30H30O4
Molecular Weight (g/mol) 454.566
InChI Key KMKBEESNZAPKMP-UHFFFAOYSA-N
Synonym biphenylindanone a, bina, biphenyl-indanone a, 3'-2-cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1h-inden-5-yl oxy methyl-1,1'-biphenyl-4-carboxylic acid, 3'-2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1h-inden-5-yl oxy methyl-1,1'-biphenyl-4-carboxylic acid, d07mhl, mrlsd 230, 4-3-2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl oxymethyl phenyl benzoic acid, biphenyl-indanone a hplc , powder, 4-3-2-cyclopentyl-6,7-dimethyl-1-oxo-indan-5-yl oxymethyl phenyl benzoic acid
PubChem CID 9868580
IUPAC Name 4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid
SMILES CC1=C(C=C2CC(C(=O)C2=C1C)C3CCCC3)OCC4=CC=CC(=C4)C5=CC=C(C=C5)C(=O)O

Specifications

Quantity 10 mg
Formula Weight 454.56
Percent Purity >98%
Chemical Name or Material BINA

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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