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AdipoGen Bisindolylmaleimide I free b

Chemical. CAS 133052-90-1. Formula C25H24N4O2. MW 412.5. Cell permeable kinase inhibitor with improved selectivity for protein kinase C PKC Ki = 10 nM. Competetive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 GSK-3 inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
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