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Bumetanide, 98+%, Thermo Scientific Chemicals

Catalog No. AAJ6230206
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Inhibitor of the sodium-potassium-chloride cotransporter

Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.

Chemical Identifiers

CAS

28395-03-1

Molecular Formula

C17H20N2O5S

Molecular Weight (g/mol)

364.416

MDL Number

MFCD00078949

InChI Key

MAEIEVLCKWDQJH-UHFFFAOYSA-N

Synonym

bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum

PubChem CID

2471

ChEBI

CHEBI:3213

IUPAC Name

3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid

SMILES

CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Specifications

Melting Point

230°C to 231°C

Color

White

Quantity

5 g

Merck Index

14,1484

Solubility Information

Soluble in ethanol (10mg/ml),DMSO (25mg/ml),acetone,benzene,methanol,propylene glycol,and water (<1mg/ml).

Formula Weight

364.4

Percent Purity

≥98%

Physical Form

Solid

Chemical Name or Material

Bumetanide

EINECSNumber

249-004-6

RTECSNumber

DG4910000

TSCA

No

Recommended Storage

Ambient temperatures
SDS

RUO – Research Use Only

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