Bupropion hydrochloride, 99%, Thermo Scientific Chemicals

Description

A selective inhibitor of dopamine uptake

Bupropion HC is used as an inhibitor of dopamine and SLC6A2. Bupropion is efficacious as an antidepressant because of its effects on nicotinic receptors, it is also used to promote smoking cessation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bupropion HC is used as an inhibitor of dopamine and SLC6A2. Bupropion is efficacious as an antidepressant because of its effects on nicotinic receptors, it is also used to promote smoking cessation.

Solubility
Soluble in water (>25 mg/ml), ethanol 193mg/ml, 0.1 N HCl 333 mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 31677-93-7
• Molecular Formula: C13H19Cl2NO
• Molecular Weight (g/mol): 276.201
• MDL Number: MFCD00055209
• InChI Key: HEYVINCGKDONRU-UHFFFAOYSA-N
• Synonym: bupropion hydrochloride, wellbutrin, 2-tert-butylamino-1-3-chlorophenyl propan-1-one hydrochloride, bupropion hcl, zyban, wellbutrin xl, bupropion hydrocloride, wellbutrin sr, budeprion, forfivo xl
• PubChem CID: 62884
• IUPAC Name: 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydrochloride
• SMILES: CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl

• Melting Point: 233°C to 234°C
• Color: White
• Quantity: 250 mg
• Merck Index: 14,1499
• Solubility Information: Soluble in water (>25mg/ml),ethanol 193mg/ml,0.1 N HCl 333mg/ml
• Formula Weight: 276.2
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: Bupropion hydrochloride

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
EINECSNumber	250-759-9
RTECSNumber	UG8858000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only