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Tocris Bioscience™ BVT 948
Non-competitive protein tyrosine phosphatase inhibitor
Supplier: Tocris Bioscience™ 2176/10
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Description
BVT 948 is a non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Also inhibits several cytochrome P450 isoforms (IC50 <10 μM).Specifications
| >98% | |
| BVT 948 | |
| BVT 948 |
| 10 mg | |
| 241.25 |
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