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Thermo Scientific Chemicals Calpeptin, ≥98%
Calpeptin is used to to inhibit the activities of cathepsin L and calpain-1. Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. It acts as an inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. It is shown to preferentially inhibit a subset of protein-tyrosine phosphatases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Specifications
Quantity
10 mg
Description
White
Content And Storage
-30°C to -10°C
For Use With (Application)
Inhibitor of the calcium-dependent protease calpain and cathepsin L
Formula Weight
362.50g/mol
Solubility
Soluble in DMSO at 15mg/ml
Product Type
Signal Transduction Reagent
Form
Powder
InChI Key
PGGUOGKHUUUWAF-ROUUACIJSA-N
SMILES
CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O
Recommended Storage
Store at -20°C
RUO – Research Use Only
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