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Thermo Scientific Chemicals Calpeptin, ≥98%

Catalog No. AAJ60481MA
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Inhibitor of the calcium-dependent protease calpain and cathepsin L

Calpeptin is used to to inhibit the activities of cathepsin L and calpain-1. Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. It acts as an inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. It is shown to preferentially inhibit a subset of protein-tyrosine phosphatases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

CAS

117591-20-5

Molecular Formula

C20H30N2O4, C20H30N2O4

Synonym

N-Benzyloxycarbonyl-L-leucyl-norleucinal; Z-Leu-norleucinal

Specifications

Quantity

10 mg

Description

White

Content And Storage

-30°C to -10°C

For Use With (Application)

Inhibitor of the calcium-dependent protease calpain and cathepsin L

Formula Weight

362.50g/mol

Solubility

Soluble in DMSO at 15mg/ml

Product Type

Signal Transduction Reagent

Form

Powder

InChI Key

PGGUOGKHUUUWAF-ROUUACIJSA-N

SMILES

CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O

IUPAC Name

benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxohexan-2-yl]carbamoyl}butyl]carbamate

Molecular Weight (g/mol)

362.47

Assay

≥98%

Recommended Storage

Store at -20°C

RUO – Research Use Only

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