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CD11a (LFA-1A) Mouse, anti-Human, RB780, Clone: HI111, BD Horizon™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 568776
This item is not returnable.
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Description
The HI111 monoclonal antibody specifically binds to CD11a, the 180 kDa integrin α chain. This type I transmembrane glycoprotein associates with CD18 (integrin β2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50).
Specifications
| CD11a (LFA-1A) | |
| HI111 | |
| Aqueous buffered solution containing ≤0.09% sodium azide | |
| 100 Tests | |
| Secondary | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| RB780 | |
| Mouse | |
| RUO | |
| 3683 | |
| Refrigerate (2°C to 8°C) |
Product Title
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