CD200 Mouse anti-Human, Clone: 5F3D6, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-106-0716 Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More	Proteintech Group Inc 662821IG150UL	150 μL

Description

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.

Specifications

• Antigen: CD200
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Purification Method: Protein G

• Concentration: 0.63 mg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Isotype: IgG1