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CD3 Mouse, anti-Human, RB780, Clone: UCHT1 (also known as UCHT-1; UCHT 1), BD Horizon™
Mouse Monoclonal Antibody
$152.70 - $327.50
Specifications
| Antigen | CD3 |
|---|---|
| Clone | UCHT1 (also known as UCHT-1; UCHT 1) |
| Applications | Flow Cytometry |
| Conjugate | RB780 |
| Host Species | Mouse |
Description
The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.
Specifications
| CD3 | |
| Flow Cytometry | |
| Mouse | |
| Human | |
| 916 | |
| IgG1 κ | |
| Refrigerate (2°C to 8°C) |
| UCHT1 (also known as UCHT-1; UCHT 1) | |
| RB780 | |
| RUO | |
| Aqueous buffered solution containing ≤0.09% sodium azide | |
| Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor | |
| Secondary |
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