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CDPPB, Tocris Bioscience™

Catalog No. p-4783838 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Positive allosteric modulator of mGlu5 receptors

Brain penetrant, selective positive allosteric modulator at the mGlu5 receptor (EC50 values are 10 and 20 nM for human and rat receptors respectively). Antipsychotic; reverses amphetamine-induced locomotor activity and amphetamine-induced deficits in prepulse inhibition in rats.

Chemical Identifiers

CAS 781652-57-1
Molecular Formula C23H16N4O
Molecular Weight (g/mol) 364.408
InChI Key BKUIZWILNWHFHD-UHFFFAOYSA-N
Synonym cdppb, 3-cyano-n-1,3-diphenyl-1h-pyrazol-5-yl benzamide, mglur5 ligand, cdppb, d0d4hg, d0m5hy, 3-cyano-n-2,5-di phenyl pyrazol-3-yl benzamide, 3-cyano-n-2,5-diphenyl-2h-pyrazol-3-yl-benzamide
PubChem CID 11245456
IUPAC Name 3-cyano-N-(2,5-diphenylpyrazol-3-yl)benzamide
SMILES C1=CC=C(C=C1)C2=NN(C(=C2)NC(=O)C3=CC=CC(=C3)C#N)C4=CC=CC=C4

Specifications

Quantity 10 mg
Formula Weight 364.4
Percent Purity >98%
Chemical Name or Material CDPPB

Safety and Handling

Recommended Storage Store at +4°C
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