Chloramphenicol (Crystalline Powder), Fisher BioReagents

For selecting transformed cells containing chloramphenicol resistance genes

Used as a selection agent for transformed cells containing chloramphenicol resistance genes. Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition).

Chemical Identifiers

CAS

56-75-7

Molecular Formula

C11H12Cl2N2O5

Molecular Weight (g/mol)

323.126

InChI Key

WIIZWVCIJKGZOK-RKDXNWHRSA-N

Synonym

Chloromycetin, D-(?)-threo-2, 2-Dichloro-N-[?-hydroxy-?-(hydroxymethyl)-?-(4-nitrophenyl)ethyl]acetamide

PubChem CID

5959

ChEBI

CHEBI:17698

IUPAC Name

2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

SMILES

C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

Type

Chloramphenicol

Physical Form

Solid

pH

5 to 7

Melting Point

149°C

Packaging

Poly Bottle

Specific Rotation

Inclusive between 17° (+ or -)

Color

White

Quantity

100 g

Assay Percent Range

97%

Merck Index

15, 2077

Formula Weight

323.13

Chemical Name or Material

Chloramphenicol

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview
Suspect cancer hazard. May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Immediate medical attention is required. Immediate medical attention is required. Do not induce vomiting.

NFPA

Health:2
Flammability:0
Instability:0

Recommended Storage

RT

SDS

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview
Suspect cancer hazard. May cause skin, eye, and respiratory tract irritation. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artifici. Immediate medical attention is required. Immediate medical attention is required. Do not induce vomiting.

NFPA

Health:2
Flammability:0
Instability:0

Recommended Storage

RT

SDS