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Thermo Scientific Chemicals Chloroform, Molecular Biology Reagent
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
Solubility
Soluble in water at 20°C 8 g/L.
Notes
Stabilized with approx. 50 ppm amylene
Specifications
Melting Point
-63°C
Color
Colorless
Density
1.492 g/mL
Boiling Point
61°C
Quantity
1 L
Odor
Characteristic
Physical Form
Liquid
Refractive Index
1.446
UN Number
UN1888
Beilstein
1731042
Hazard Category
H302-H315-H319-H331-H335-H336-H351-H361d-H373
Hazard Statement
GHS H Statement
H351-H373-H302-H315
Suspected of causing cancer.
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
Causes skin irritation.
Precautionary Statement
P201-P202-P260-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
DOTInformation
Transport Hazard Class: 6.1; Packaging Group: III; Proper Shipping Name: CHLOROFORM
EINECSNumber
200-663-8
RTECSNumber
FS9100000
TSCA
Yes
Recommended Storage
Ambient temperatures
RUO – Research Use Only
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