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AdipoGen Citrinin
SDP

Supplier:  AdipoGen AGCN20101M001

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Chemical. CAS 518-75-2. Formula C13H14O5. MW 250.3. Isolated from Penicillium citrinum strain FKI-4836. Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore MPTP activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species ROS. Induces cell cycle arrest at the G0/G1 and G2/M phase.

Catalog No. 50-256-2660


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