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Tocris Bioscience™ Cladribine

Deoxyadenosine analog; pro-apoptotic

Specifications

Purity >99%
Product Type Cladribine
Molecular Weight (g/mol) 285.69
Inhibitors Cladribine
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
52-921-0
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Tocris Bioscience™
5292/10 		10 mg N/A N/A N/A
52-925-0
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Tocris Bioscience™
5292/50 		50 mg N/A N/A N/A
Description

Description

Adenosine deaminase (ADA)-resistant analog of deoxyadenosine. Exhibits anti-leukemic activity; Inhibits cell growth of lymphoid and myeloid neoplasm (IC50 = 20 - 87 nM). Pro-apoptotic; induces DNA double-strand breaks. Also inhibits ribonuclease reductase (IC50 = 0.11 - 0.28 μM). Displays activity in vitro and in vivo. Orally bioavailable.
Specifications

Specifications

>99%
Cladribine
285.69
Cladribine
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For Research Use Only

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