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Clofibrate, 95+%, Thermo Scientific Chemicals

Catalog No. AAJ6034222
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It is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well. Clofibrate is a ligand agonist for PPARα (peroxisome proliferator-activated receptor α), or an inducer of cytochromes P450’s CYP4A1 and CYP4A3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble to 100 mM in DMSO.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, bases. Store in refrigerator.

Chemical Identifiers

CAS

637-07-0

Molecular Formula

C12H15ClO3

Molecular Weight (g/mol)

242.70

MDL Number

MFCD00000615

InChI Key

KNHUKKLJHYUCFP-UHFFFAOYSA-N

Synonym

clofibrate, ethyl clofibrate, clofibratum, clofibrato, atromid-s, miscleron, atromid, liprin, epib, angiokapsul

PubChem CID

2796

ChEBI

CHEBI:3750

IUPAC Name

ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

SMILES

CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1

Specifications

Density

1.14

Boiling Point

154°C to 156°C

Flash Point

113°C (235°F)

Refractive Index

1.5

Quantity

100 g

UN Number

UN3082

Beilstein

1913459

Merck Index

14,2377

Solubility Information

Soluble to 100 mM in DMSO.

Formula Weight

242.7

Percent Purity

≥95%

Physical Form

Liquid

Chemical Name or Material

Clofibrate

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Hazard Category

H302-H315-H318-H335

Hazard Statement

GHS H Statement
H318-H302-H335-H315
Causes serious eye damage.
Harmful if swallowed.
May cause respiratory irritation.
Causes skin irritation.

Precautionary Statement

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c

DOTInformation

Transport Hazard Class: 9; Packing Group: III; Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.

EINECSNumber

211-277-4

RTECSNumber

UE9480000

TSCA

No

Recommended Storage

Keep cold
SDS

RUO – Research Use Only

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