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Clotrimazole, Tocris Bioscience™

Catalog No. 409650 Shop All R&D Systems Products
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Cytochrome P450 inhibitor; antifungal

Imidazole antimycotic and cytochrome P450 inhibitor. Inhibits Ca2+-activated K+ current (IC50 = 3 μM) and L-type Ca2+ current; increases the firing rate of action potentials. Exhibits antiproliferative activity in vitro and in vivo. Also an inverse agonist of the human constitutive androstane receptor (hCAR).

Chemical Identifiers

CAS

23593-75-1

Molecular Formula

C22H17ClN2

Molecular Weight (g/mol)

344.842

InChI Key

VNFPBHJOKIVQEB-UHFFFAOYSA-N

Synonym

clotrimazole, lotrimin, canesten, mycelex, mycosporin, empecid, clotrimazol, mykosporin, gyne lotrimin, chlotrimazole

PubChem CID

2812

ChEBI

CHEBI:3764

IUPAC Name

1-[(2-chlorophenyl)-diphenylmethyl]imidazole

SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Specifications

Quantity

50 mg

Formula Weight

344.84

Percent Purity

>99%

Chemical Name or Material

Clotrimazole

Recommended Storage

Store at Room Temperature
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