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CU CPT 22, Tocris Bioscience™

Catalog No. 488450 Shop All R&D Systems Products
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Selective TLR1/2 inhibitor

Selective toll-like receptor 1/2 (TLR1/2) inhibitor (IC50 = 0.58 μM). Exhibits no activity at TLR2/TLR6, TLR3, TLR4 and TLR7 or a panel of 10 representative kinases. Inhibits the release of proinflammatory cytokines TNF-α and IL-1β.

Chemical Identifiers

CAS

1416324-85-0

Molecular Formula

C19H22O7

Molecular Weight (g/mol)

362.378

InChI Key

UBQFTTUFRSSOHE-UHFFFAOYSA-N

Synonym

cu cpt 22, cu-cpt-22, cu-cpt hplc, 3,4,6-trihydroxy-2-methoxy-5-oxo-5h-benzocycloheptene-8-carboxylic acid hexyl ester, hexyl 1,2,8-trihydroxy-3-methoxy-9-oxobenzo 7 annulene-6-carboxylate

PubChem CID

71503400

IUPAC Name

hexyl 3,4,5-trihydroxy-2-methoxy-6-oxobenzo[7]annulene-8-carboxylate

SMILES

CCCCCCOC(=O)C1=CC(=O)C(=C2C(=C1)C=C(C(=C2O)O)OC)O

Specifications

Quantity

50 mg

Formula Weight

362.37

Percent Purity

>98%

Chemical Name or Material

CU CPT 22

Recommended Storage

Store at -20°C
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