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CU CPT 4a, Tocris Bioscience™

Catalog No. 488350 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective TLR3 inhibitor

Selective TLR3 inhibitor (IC50 = 3.44 μM in RAW 264.7 cells); suppresses downstream signaling pathways mediated by the TLR3/dsRNA complex, inhibiting TNF-α and IL-1β production in whole cells. Reduces death of crypt cells and improves gastrointestinal syndrome in mice.

Chemical Identifiers

CAS 1279713-77-7
Molecular Formula C18H13ClFNO3S
Molecular Weight (g/mol) 377.814
InChI Key IAASQMCXDRISAV-CYBMUJFWSA-N
Synonym cu cpt 4a, n-3-chloro-6-fluorobenzo b thien-2-yl carbonyl-d-phenylalanine, n-3-chloro-6-fluorobenzo b thiophene-2-yl carbonyl-d-phenylalanine, r-2-3-chloro-6-fluorobenzo b thiophene-2-carboxamido-3-phenylpropanoic acid
PubChem CID 53242268
IUPAC Name (2R)-2-[(3-chloro-6-fluoro-1-benzothiophene-2-carbonyl)amino]-3-phenylpropanoic acid
SMILES C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C2=C(C3=C(S2)C=C(C=C3)F)Cl

Specifications

Quantity 50 mg
Formula Weight 377.82
Chemical Name or Material CU CPT 4a

Safety and Handling

Recommended Storage Store at +4°C
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