Dexamethasone, 98%, Thermo Scientific Chemicals

Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.

Solubility
Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.

Notes
Store in cool place. Light sensitive. Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS

50-02-2

Molecular Formula

C22H29FO5

Molecular Weight (g/mol)

392.47

MDL Number

MFCD00064136

InChI Key

UREBDLICKHMUKA-CXSFZGCWSA-N

Synonym

dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol

PubChem CID

5743

ChEBI

CHEBI:41879

IUPAC Name

(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

Melting Point

∽260°C (decomposition)

Assay Percent Range

0.98

Quantity

1 g

Beilstein

2066651

Sensitivity

Light sensitive

Merck Index

142943

Solubility Information

Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.

Formula Weight

392.47

Percent Purity

98%

Chemical Name or Material

Dexamethasone

Hazard Category

Carcinogenicity (category 2)

Hazard Statement

Suspected of causing cancer

EINECSNumber

200-003-9

RTECSNumber

TU3980000

TSCA

Yes

Recommended Storage

Ambient temperatures

SDS

Hazard Category

Carcinogenicity (category 2)

Hazard Statement

Suspected of causing cancer

EINECSNumber

200-003-9

RTECSNumber

TU3980000

TSCA

Yes

Recommended Storage

Ambient temperatures

SDS

RUO – Research Use Only