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  7. Dexmedetomidine hydrochloride, Tocris Bioscience™

Dexmedetomidine hydrochloride, Tocris Bioscience™

Catalog No. p-4783904 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)

Dexmedetomidine hydrochloride is an active isomer of medetomidine, a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). Displays greater selectivity over α1-adrenoceptors than Clonidine (Cat. No. 0690) and UK 14,304 (1620-, 220- and 300-fold respectively). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects.

Racemate also available.

Chemical Identifiers

CAS 145108-58-3
Molecular Formula C13H17ClN2
Molecular Weight (g/mol) 236.743
InChI Key VPNGEIHDPSLNMU-MERQFXBCSA-N
Synonym dexmedetomidine hydrochloride, dexmedetomidine hcl, precedex, 4-s-alpha,2,3-trimethylbenzyl imidazole monohydrochloride, unii-1018wh7f9i, dexmedetomidine hcl precedex, s-5-1-2,3-dimethylphenyl ethyl-1h-imidazole hydrochloride, dexdor, 4-1s-1-2,3-dimethylphenyl ethyl-1h-imidazole hydrochloride
PubChem CID 6918081
ChEBI CHEBI:31472
IUPAC Name 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole;hydrochloride
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl

Specifications

Quantity 10 mg
Formula Weight 236.74
Percent Purity 98%
Chemical Name or Material Dexmedetomidine hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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