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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Catalog No. ICN16011010 Shop All MP Biomedicals, Inc Products
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Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution

Specifications

Color

White

Chemical Name or Material

Dextran Sulfate Sodium Salt

pH

5 to 7.11 (1% aqueous solution)

Physical Form

Powder

CAS

9011-18-1

Boiling Point

310°C

Melting Point

92°C

Molecular Formula

(C6H7O5)m(C6H7O5)n

MDL Number

MFCD00081551

Solubility Information

Soluble in water

Quantity

10 g

InChI Key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

SMILES

*-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]

IUPAC Name

Dextran sulfate sodium salt

Molecular Weight (g/mol)

40,000

For Use With (Application)

Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation

Grade

Colitis Grade

Moisture

<10%

Packaging

Plastic Container

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.

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