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Dizocilpine maleate, 99+%, Thermo Scientific Chemicals

Catalog No. AAJ63917MF
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NMDA receptor antagonist that prevents calcium flux

Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

Solubility
Soluble in ethanol.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Chemical Identifiers

CAS

77086-22-7

Molecular Formula

C20H19NO4

Molecular Weight (g/mol)

337.375

MDL Number

MFCD00082465

InChI Key

QLTXKCWMEZIHBJ-PJGJYSAQSA-N

Synonym

dizocilpine maleate, +-mk-801 hydrogen maleate, +-mk 801 maleate, dizocilpine hydrogen maleate, unii-6lr8c1b66q, dizocilpine maleate usan, dsstox_cid_25785, dsstox_rid_81126

PubChem CID

6420042

SMILES

CC12C3=CC=CC=C3CC(N1)C4=CC=CC=C24.C(=CC(=O)O)C(=O)O

Specifications

Color

White

Quantity

50 mg

Merck Index

14,3386

Solubility Information

Soluble in ethanol.

Formula Weight

337.37

Percent Purity

≥99%

Physical Form

Crystalline Powder

Chemical Name or Material

Dizocilpine maleate

EINECSNumber

278-614-5

RTECSNumber

HP1093575

TSCA

No

Recommended Storage

Keep cold

RUO – Research Use Only

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