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  7. Domperidone, Thermo Scientific Chemicals

Domperidone, Thermo Scientific Chemicals

Catalog No. p-7042762
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Quantity:
50 mg
100 mg
500 mg

Description

Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier

Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.

Solubility
Slightly soluble in water.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Chemical Identifiers

CAS 57808-66-9
Molecular Formula C22H24ClN5O2
Molecular Weight (g/mol) 425.917
MDL Number MFCD00069256
InChI Key FGXWKSZFVQUSTL-UHFFFAOYSA-N
Synonym domperidone, motilium, nauzelin, domperidonum, domperidona, domperidon, domperidonum inn-latin, domperidona inn-spanish, motillium, motinorm
PubChem CID 3151
ChEBI CHEBI:31515
IUPAC Name 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
SMILES C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O

Specifications

Melting Point 243°C
Color White
Quantity 100 mg
Merck Index 14,3418
Solubility Information Slightly soluble in water.
Formula Weight 425.91
Physical Form Crystalline Powder
Chemical Name or Material Domperidone

Safety and Handling

Hazard Category H361
Hazard Statement GHS H Statement
H361
Suspected of damaging fertility or the unborn child.
Precautionary Statement P201-P202-P281-P308+P313-P501c
EINECSNumber 260-968-7
RTECSNumber DE2275900
TSCA No
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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