Doxorubicin Hydrochloride, Fisher BioReagents

Doxorubicin Hydrochloride

Doxorubicin HCL is a chemotherapeutic agent. Antitumor, immunosuppressive, and antibiotic agent. It blocks RNA polymerase and reverse transcriptase. Also inhibits nucleic acid synthesis.

Chemical Identifiers

CAS

25316-40-9

Molecular Formula

C27H30ClNO11

Molecular Weight (g/mol)

579.98

MDL Number

MFCD00077757,MFCD00077757,MFCD00941448

InChI Key

MWWSFMDVAYGXBV-FGBJBKNOSA-N

Synonym

doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs

PubChem CID

129626538

IUPAC Name

(7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

SMILES

[H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O

Decomposition Information

216°C

Melting Point

216°C

Color

Orange

Assay Percent Range

(by HPLC): ≥95%

Packaging

Amber Glass

Quantity

10 mg

Merck Index

15, 3487

Solubility Information

Soluble in water

Formula Weight

580

Physical Form

Powder or Solid

Chemical Name or Material

Doxorubicin Hydrochloride

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview
May cause cancer. Risk of serious damage to eyes. Irritating to respiratory system and skin. May cause heritable genetic damage. Possible risk of impaired fertility. Possible risk of harm to the unborn child. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Immediate medical attention is required. Move to fresh air.

NFPA

Health:2
Flammability:1
Instability:0

Recommended Storage

2° to 8°C

SDS

Hazard Statement

WARNING!

Precautionary Statement

Emergency Overview
May cause cancer. Risk of serious damage to eyes. Irritating to respiratory system and skin. May cause heritable genetic damage. Possible risk of impaired fertility. Possible risk of harm to the unborn child. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Immediate medical attention is required. Move to fresh air.

NFPA

Health:2
Flammability:1
Instability:0

Recommended Storage

2° to 8°C

SDS