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  8. E-4031 dihydrochloride, Tocris Bioscience™

E-4031 dihydrochloride, Tocris Bioscience™

Catalog No. 180850 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

Selective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr). Reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na+ or Ca2+ inward currents. Class III antiarrhythmic agent.

Chemical Identifiers

CAS 113559-13-0
Molecular Formula C21H29Cl2N3O3S
Molecular Weight (g/mol) 474.44
MDL Number MFCD01754739
InChI Key ZQBNWMFBOSOOLX-UHFFFAOYSA-N
Synonym e-4031 dihydrochloride, 1-2-6-methyl-2-pyridyl ethyl-4-4-methylsulfonylaminobenzoyl piperidine dihydrochloride, methanesulfonamide, n-4-1-2-6-methyl-2-pyridinyl ethyl-4-piperidinyl carbonyl phenyl-,dihydrochloride, n-4-1-2-6-methyl-2-pyridinyl ethyl-4-piperidinyl carbonyl phenyl methanesulfonamide dihydrochloride, n-4-1-2-6-methylpyridin-2-yl ethyl piperidine-4-carbonyl phenyl methanesulfonamide dihydrochloride, e-4031 free, c21h27n3o3s.2clh
PubChem CID 3087190
IUPAC Name dihydrogen N-(4-{1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl}phenyl)methanesulfonamide dichloride
SMILES [H+].[H+].[Cl-].[Cl-].CC1=CC=CC(CCN2CCC(CC2)C(=O)C2=CC=C(NS(C)(=O)=O)C=C2)=N1

Specifications

Quantity 50 mg
Formula Weight 474.44
Percent Purity >98%
Chemical Name or Material E-4031 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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