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List Biological Laboratories Inc FHA (Filamentous Hemaglutinin from B. pertussis), 25 μg in 0.25 mL

Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development project! FHA is a key virulence factor to establishing Bordetella pertussis infection. FHA, which is both surface-associated and secreted by B. pertussis, is a large (220kDa) multifunctional protein which promotes the attachment of the bacteria through several binding domains. FHA acts through multiple pathways to modulate the host immune response; an example of this type of activity is induction in macrophages of the secretion of both pro-inflammatory and anti-inflammatory cytokines. Because FHA is highly immunogenic, it is included in many acellular vaccines. List Labs FHA is purified from the native B. pertussis strain 165.
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