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Fluoxetine hydrochloride, Tocris Bioscience™

Catalog No. 092750 Shop All R&D Systems Products
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5-HT reuptake inhibitor

Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor. Binds to the human 5-HT transporter with a Ki of 0.9 nmol/l and is between 150- and 900-fold selective over 5-HT1A, 5-HT2A, H1, α1, α2-adrenergic, and muscarinic receptors. Antidepressant. Induces differentiation of neuronal precursors, enhancing neuronal characteristics. Fluoxetine also inhibits assembly and activation of the NLRP3-ASC inflammasome and prevents degeneration of retinal pigmented epithelium (RPE) cells in an animal model of dry age-related macular degeneration (AMD).

Chemical Identifiers

CAS

56296-78-7

Molecular Formula

C17H19ClF3NO

Molecular Weight (g/mol)

345.79

InChI Key

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Synonym

fluoxetine hydrochloride, prozac, fluoxetine hcl, sarafem, flunirin, fluoxeren, adofen, fluctin, lovan

PubChem CID

62857

IUPAC Name

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride

SMILES

CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl

Specifications

Quantity

50 mg

Formula Weight

345.78

Percent Purity

>99%

Chemical Name or Material

Fluoxetine hydrochloride

Recommended Storage

Store at Room Temperature
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