Forskolin, 98+%, Thermo Scientific Chemicals

Forskolin, CAS # 66575-29-9, is a diterpenoid compound isolated from Indian Coleus that acts as a strong activator of the adenylate cyclase system.

Forskolin acts as an adenylyl cyclase activator. It is used in the treatment of hypertension, asthma, eczema, psoriasis, congestive heart failure, angina, stomachache, gastric and intestinal spasm. It also plays an important role in the treatment of rheumatism, heart, blood and circulation conditions and cancers. It is used to induce menstruation and as an oral contraceptive.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Forskolin is a diterpenoid and cyclic ketone, found naturally as a plant metabolite

• It is a protein kinase A agonist and a cyclic ketone • Forskolin is an antihypertensive and muscle relaxant; it can also promote the release of pituitary hormones and prevent platelet aggregation

Application

• Forskolin assists in neuron differentiation in vitro

• Useful for studies of cell metabolism and development; there is some evidence of its usefulness in the study of glaucoma

• It is intended for cell culture and biochemistry applications

Chemical Identifiers

CAS

66575-29-9

Molecular Formula

C22H34O7

Molecular Weight (g/mol)

410.507

MDL Number

MFCD00082317

InChI Key

OHCQJHSOBUTRHG-KGGHGJDLSA-N

Synonym

forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish

PubChem CID

47936

ChEBI

CHEBI:42471

IUPAC Name

[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate

SMILES

CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O

Color

White

Quantity

10 mg

Beilstein

1692716

Merck Index

14,2476

Solubility Information

Soluble in ethanol,dimethylsulfoxide and chloroform; Insolule in water.

Formula Weight

410.51

Percent Purity

≥98%

Physical Form

Solid

Chemical Name or Material

Forskolin

Hazard Category

H312

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P280-P302+P352-P312-P363-P501c

EINECSNumber

266-410-9

RTECSNumber

QL6150000

TSCA

No

Recommended Storage

Store at -20°C

SDS

Hazard Category

H312

Hazard Statement

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Precautionary Statement

P280-P302+P352-P312-P363-P501c

EINECSNumber

266-410-9

RTECSNumber

QL6150000

TSCA

No

Recommended Storage

Store at -20°C

SDS

RUO – Research Use Only