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Tecan FULLY REDUCED LPS-FREE 500UG
HMGB1, Fully reduced, LPS-free. 500 �g . HMGB1, a nuclear protein released passively by necrotic cells, retained by apoptotic cells, and secreted actively by inflammatory cells. Two different activities of HMGB1 as a chemoattractant of motile cells and as inducer of cytokines have been attributed to different biochemical forms. Chemokine-HMGB1 (the form with chemoattractant activity) is completely reduced, while Cytokine-HMGB1 contains a disulfide bond between C23 and C45. Key words: attracting inflammatory cells, tissue repair, attracting stem cells, promoting their proliferation, dendritic cells, functional maturation and migration to lymph nodes, LPS, single-stranded DNA, IL-1beta. The Chemokine-HMGB1 we provide is the natural protein, with no tags or additional amino acids. Produced in E.coli from an expression plasmid coding for the rat protein. Distributed by IBL. Research Use Only.
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