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Fumitremorgin C, Tocris Bioscience™

Catalog No. 2876250U Shop All R&D Systems Products
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Quantity:
250 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of BCRP-mediated multidrug resistance

Chemosensitizing agent; selectively reverses BCRP-mediated multidrug resistance to mitoxantrone (Cat. No. 4250), doxorubicin (Cat. No. 2252) and topotecan (Cat. No. 4562) in transfected MCF-7 cells. Does not reverse resistance in P-gp- or MRP-positive cells. Analog ( Ko 143, Cat. No. 3241) also available.

Chemical Identifiers

CAS 118974-02-0
Molecular Formula C22H25N3O3
Molecular Weight (g/mol) 379.46
InChI Key DBEYVIGIPJSTOR-FHWLQOOXSA-N
Synonym fumitremorgin c, fumitremorgin c, aspergillus. fumigatus, fumitremorgin-c, sm-q, 5as,12s,14as-9-methoxy-12-2-methylprop-1-en-1-yl-1,2,3,5a,6,11,12,14a-octahydro-5h,14h-pyrrolo 1,2:4',5' pyrazino 1',2':1,6 pyrido 3,4-b indole-5,14-dione, 5h,14h-pyrrolo 1,2:4',5' pyrazino 1',2':1,6 pyrido 3,4-b indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-2-methyl-1-propen-1-yl-, 5as,12s,14as, fumitremorgin c, from neosartorya fischeri hplc and tlc , film, 1s,12s,15s-7-methoxy-12-2-methylprop-1-en-1-yl-10,13,19-triazapentacyclo 11.7.0.0; 3,11 .0; 4,9 .0; 15,19 icosa-3 11 ,4,6,8-tetraene-14,20-dione, 5as,12s,14as-1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-2-methyl-1-propen-1-yl-5h,14h-pyrrolo 1,2:4',5' pyrazino 1',2':1,6 pyrido 3,4-b indole-5,14-dione
PubChem CID 403923
ChEBI CHEBI:72763
SMILES CC(=CC1C2=C(CC3N1C(=O)C4CCCN4C3=O)C5=C(N2)C=C(C=C5)OC)C

Specifications

Quantity 250 μg
Formula Weight 379.45
Percent Purity >98%
Chemical Name or Material Fumitremorgin C

Safety and Handling

Recommended Storage Store at +4°C
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