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TARGETMOL CHEMICALS INC GIGANTOL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Gigantol is a novel inhibitor of the Wnt/(beta)-catenin pathway. It inhibits Wnt/(beta)-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic (beta)-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases it shows the protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-(kappa)B signaling pathway.Gigantol also shows (alpha)-glucosidase inhibitory activity. purity: 99%
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