Thermo Scientific™ GlycanPac™ AXR-1 HPLC Columns

Get ultra-high resolution and selectivity for both labeled and native glycans using this HPLC/UHPLC column. It's compatible with MS and fluorescence detection.

Get industry-leading, ultra-high resolution of labeled and native glycans for structural characterization and quantification using the Thermo Scientific™ GlycanPac™ AXR-1 LC Columns. This high-performance, silica-based chromatography column achieves mixed-mode separation using a combination of charge, isomer structure, and size. Now there's a column with unique selectivity to analyze biologically important glycans. The GlycanPac AXR-1 column is available in multiple HPLC and UHPLC formats and is compatible with fluorescence or mass spectrometry (MS) detection.

Exceptional Glycan Selectivity with Industry-Leading Resolution

Ultra-high resolution and selectivity of glycans are attributed to the GlycanPac AXR-1 column's innovative mixed-mode surface chemistry, which combines:

• WAX functionality for retention of negatively charged glycans, with separation in order of increasing charge
• Reversed-phase functionality for same-charge glycans, with separation according to isomerism and size

Reliable Column Performance

This high-purity spherical silica column is designed and tested for HPLC and UHPLC methods using either fluorescence or MS detection applications. The GlycanPac AXR-1 column uses volatile aqueous buffers (e.g., ammonium acetate or ammonium formate) and acetonitrile, presenting the eluting glycans ready for introduction into MS instruments.

Available in Multiple Formats

• Use 1.9μm columns for UHPLC applications and 3μm columns for HPLC applications
• Select from a variety of dimensions to support the resolution, throughput, or instrumental requirements required for your application
• Protect the analytical column with GycanPac AXR-1 Guard columns

Column Chemistry

WAX and RP Mixed Mode

Column Format

Analytical Column

Diameter (Metric)

2.1 mm

Flow Rate

0.2 to 0.4 mL/min

Length (Metric)

150 mm

Max. Pressure

10000 psi (690 bar)

Particle Shape

Spherical, high purity, porous

Particle Size

1.9 μm

pH

2 to 8

Pore Size

175 Å

Solvents

Compatible with 0 to 100% aqueous and common HPLC solvents

Surface Area

220 m²/g

Temperature

60°C

Stationary Phase

Proprietary

Product Line

GlycanPac

Packing Material

Spherical, Fully Porous, Ultrapure Silica

Column Type

Mixed Mode

Phase

Reversed Phase and Ion Exchange

Type

AnalyticalColumn

Technique

Bio-LC

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.