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Go 6983, Tocris Bioscience™

Catalog No. p-4783992 Shop All R&D Systems Products
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Quantity:
1 mg
10 mg
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This item is not returnable. View return policy

Description

Broad spectrum PKC inhibitor

Broad spectrum protein kinase C (PKC) inhibitor (IC50 values are 7, 7, 6, 10, 60 and 20000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ and PKCμ respectively). Displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury. Optimizes naïve human pluripotent stem cell growth and viability following naïve cell derivation from primed ESCs and iPSCs using naïve human stem cell medium (NHSM).

Chemical Identifiers

CAS 133053-19-7
Molecular Formula C26H26N4O3
Molecular Weight (g/mol) 442.519
InChI Key LLJJDLHGZUOMQP-UHFFFAOYSA-N
Synonym gö 6983, 3-1-3-dimethylamino propyl-5-methoxy-1h-indol-3-yl-4-1h-indol-3-yl-1h-pyrrole-2,5-dione, 2-1-3-dimethylaminopropyl-5-methoxyindol-3-yl-3-1h-indol-3-yl maleimide, gouml 6983, d06tll, go, g, 3-1-3-dimethylamino propyl-5-methoxyindol-3-yl-4-1h-indol-3-yl pyrrole-2,5-dione
PubChem CID 3499
IUPAC Name 3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
SMILES CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54

Specifications

Quantity 1 mg
Formula Weight 442.51
Percent Purity >98%
Chemical Name or Material Go 6983

Safety and Handling

Recommended Storage Store at -20°C
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