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Guanidine hydrochloride, 98%, Thermo Scientific Chemicals
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Guanidine hydrochloride is the hydrochloride salt of guanidine, an acetylcholine releasing agent
- It is a normal product of protein metabolism and is sometimes used for pyrimidine synthesis
Application
- Guanidine hydrochloride is a powerful denaturant, useful for taking nucleic acids (DNA and RNA) and proteins out of their native conformation
- Guanidine hydrochloride acts as a strong organic base at physiological pH
- It is suitable for use in protein and nucleic acid purification protocols
Specifications
Melting Point
178°C to 185°C
Density
1.344
Quantity
1000 g
Beilstein
3591990
Sensitivity
Hygroscopic
Merck Index
144562
Solubility Information
Soluble in water and ethanol.
Formula Weight
95.53
Percent Purity
98%
Chemical Name or Material
Guanidine hydrochloride
Hazard Category
Serious eye damage/eye irritation (category 2), Skin corrosion/irritation (category 2), Acute toxicity (category 4)
Hazard Statement
Causes serious eye irritation, May form combustible dust concentrations in air, Causes skin irritation, Harmful if swallowed or if inhaled
EINECSNumber
200-002-3
RTECSNumber
MF4300000
TSCA
Yes
Recommended Storage
Ambient temperatures
RUO – Research Use Only
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