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GW 441756, Tocris Bioscience™

Catalog No. p-4784007 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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Description

Potent, selective TrkA inhibitor

Potent, selective inhibitor of the NGF receptor tyrosine kinase A (TrkA) (IC50 = 2 nM). Displays > 100-fold selectivity over a range of other kinases.

Chemical Identifiers

CAS 504433-23-2
Molecular Formula C17H13N3O
Molecular Weight (g/mol) 275.311
InChI Key NXNQLECPAXXYTR-UKTHLTGXSA-N
Synonym 1,3-dihydro-3-1-methyl-1h-indol-3-yl methylene-2h-pyrrolo 3,2-b pyridin-2-one, 3e-3-1-methylindol-3-yl methylidene-1h-pyrrolo 3,2-b pyridin-2-one, e-3-1-methyl-1h-indol-3-yl methylene-1h-pyrrolo 3,2-b pyridin-2 3h-one, 3-e-1-methyl-1h-indole-3-yl methylene-2,3-dihydro-1h-pyrrolo 3,2-b pyridine-2-one
PubChem CID 22228376
IUPAC Name (3E)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
SMILES CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O

Specifications

Quantity 10 mg
Formula Weight 275.31
Percent Purity >99%
Chemical Name or Material GW 441756

Safety and Handling

Recommended Storage Store at Room Temperature
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