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GW 9662, Tocris Bioscience™

Catalog No. p-4783504 Shop All R&D Systems Products
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective covalent PPARγ antagonist

GW 9662 is a selective irreversible PPARγ antagonist (IC50 values are 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively). Blocks the inhibition of osteoclast formation induced by IL-4 in the low micromolar range (1-2 μM), therefore is more potent than BADGE. Anticancer, inhibits growth of human mammary tumor cell lines.

Chemical Identifiers

CAS 22978-25-2
Molecular Formula C13H9ClN2O3
Molecular Weight (g/mol) 276.676
InChI Key DNTSIBUQMRRYIU-UHFFFAOYSA-N
Synonym 2-chloro-5-nitrobenzanilide, 2-chloro-5-nitro-n-phenyl-benzamide, 2-chloro-5-nitro-n-4-phenylbenzamide, 2-chloro-5-nitrophenyl-n-benzamide, tocris-1508, spectrum5_001989, lopac-m-6191, d00acx, d05thb, dsstox_cid_20723
PubChem CID 644213
ChEBI CHEBI:79993
IUPAC Name 2-chloro-5-nitro-N-phenylbenzamide
SMILES C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl

Specifications

Quantity 10 mg
Formula Weight 276.68
Percent Purity >98%
Chemical Name or Material GW 9662

Safety and Handling

Recommended Storage Store at Room Temperature
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