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  8. H 89 dihydrochloride, Tocris Bioscience™

H 89 dihydrochloride, Tocris Bioscience™

Catalog No. p-4784016 Shop All R&D Systems Products
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1 mg
10 mg
50 mg
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Description

Protein kinase A inhibitor

H 89 dihydrochloride is a protein kinase A inhibitor that also inhibits several other kinases (IC50 values are 80, 120, 135, 270, 2600 and 2800 nM for S6K1, MSK1, PKA, ROCKII, PKBα and MAPKAP-K1b). Exhibits antinociceptive activity. Enhances survival and clonogenicity of dissociated human ESCs through ROCK inhibition.

Chemical Identifiers

CAS 130964-39-5
Molecular Formula C20H24BrCl2N3O3S
Molecular Weight (g/mol) 537.294
InChI Key GKFFJFGBWAGAFD-HZBIHQSRSA-N
Synonym h-89 dihydrochloride hydrate, n-2-p-bromocinnamylamino ethyl-5-isoquinolinesulfonamide dihydrochloride, c20h20brn3o2s.2clh.h2o, h-89 dihydrochloride hydrate hplc , powder, n-2-2e-3-4-bromophenyl prop-2-en-1-yl amino ethyl isoquinoline-5-sulfonamide hydrate dihydrochloride
PubChem CID 16078954
IUPAC Name N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide;hydrate;dihydrochloride
SMILES C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br.O.Cl.Cl

Specifications

Quantity 1 mg
Formula Weight 519.28
Percent Purity >99%
Chemical Name or Material H 89 dihydrochloride

Safety and Handling

Recommended Storage Store at -20°C
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