HC 030031, Tocris Bioscience™

Description

Selective TRPA1 blocker

Selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx (IC50 values are 6.2 and 5.3 μM respectively). Does not block currents mediated by TRPV1, TRPV3, TRPV4, hERG or NaV1.2 channels. Inhibits AITC- and formalin-induced flinching in vivo.

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Specifications

Chemical Identifiers

• CAS: 349085-38-7
• Molecular Formula: C18H21N5O3
• Molecular Weight (g/mol): 355.398
• InChI Key: HEQDZPHDVAOBLN-UHFFFAOYSA-N
• Synonym: 2-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7h-purin-7-yl-n-4-isopropylphenyl acetamide, 2-1,3-dimethyl-2,6-dioxopurin-7-yl-n-4-propan-2-ylphenyl acetamide, 2-1,3-dimethyl-2,6-dioxo-2,3-dihydro-1h-purin-7 6h-yl-n-4-isopropylphenyl acetamide, 2-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-yl-n-4-isopropylphenyl acetamide, 2-1,3-dimethyl-2,6-dioxopurin-7-yl-n-4-isopropylphenyl acetamide, 2-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7h-purin-7-yl-n-4-propan-2-yl phenyl acetamide, d0d6mc, hc hplc , powder, 2-1,3-dimethyl-2,6-dioxo 1,3,7-trihydropurin-7-yl-n-4-methylethyl phenyl acetamide, trpa1 inhibitor pain/inflammation , hydra biosciences/cubist pharmaceuticals
• PubChem CID: 1150897
• IUPAC Name: 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide
• SMILES: CC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C

• Quantity: 10 mg
• Formula Weight: 355.39
• Percent Purity: >99%
• Chemical Name or Material: HC 030031

Safety and Handling

Recommended Storage

Store at Room Temperature