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Heparin sodium salt, from porcine intestinal mucosa, IU≥100/mg, Thermo Scientific Chemicals
Heparin sodium salt is used as a blood anti-coagulant. It is also used as an effective inhibitor of mesenchymal cell proliferation. Further, it binds to antithrombin III, which inhibits coagulation proteases. It is used as a major component of serum free media for preventing cell aggregation. It is also used as an anti-cancer agent in in vitro cancer research.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Heparin sodium salt displays anti-coagulant activity. It can also efficiently inhibit mesenchymal cell proliferation and promotes the proliferation of primary epithelial cells
- This compound can bind to antithrombin III and inhibit coagulation proteases
Applications
- In in vitro studies, it is used as the main component of serum-free media to prevent cell aggregation
- Heparin sodium salt can also induce the growth of human embryonic stem cells in a defined serum-free medium, acting as a cofactor for a basic fibroblast growth factor (FGF-2)
- It is also applied in laboratory studies related to stem cell differentiation and growth
- In in vitro studies, this compound exhibits cytotoxic action inducing cancer cell death by interfering with transcription factor activity
Specifications
Quantity
250 mg
Merck Index
14,4653
Solubility Information
Soluble in water,dimethyl sulfoxide and ethanol.
Concentration or Composition (by Analyte or Components)
≥100 IU/mg
Chemical Name or Material
Heparin sodium salt, from porcine intestinal mucosa
RTECSNumber
MI0850000
TSCA
Yes
Recommended Storage
Keep cold
RUO – Research Use Only
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