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Heparin sodium, Thermo Scientific Chemicals
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Heparin sodium salt displays anti-coagulant activity. It can also efficiently inhibit mesenchymal cell proliferation and promotes the proliferation of primary epithelial cells
- This compound can bind to antithrombin III and inhibit coagulation proteases
Applications
- In in vitro studies, it is used as the main component of serum-free media to prevent cell aggregation
- Heparin sodium salt can also induce the growth of human embryonic stem cells in a defined serum-free medium, acting as a cofactor for a basic fibroblast growth factor (FGF-2)
- It is also applied in laboratory studies related to stem cell differentiation and growth
- In in vitro studies this compound exhibits cytotoxic action inducing cancer cell death by interfering with transcription factor activity
Specifications
Absorbance
≤0.2% as nucleotides, 0.2 max. (0.4% in water) at 260nm, Protein and nucleotide impurities:, Protein and nucleotide impurities: at 0nm
Color
White
pH
Inclusive between 5.5 (1% soln.)
Ignition Residue
Inclusive between 30%
Loss on Drying
≤8% (at 60°C for 4 hr.)
Infrared Spectrum
Pass Test
Packaging
Glass Bottle
Quantity
1 g
Merck Index
15, 4688
Percent Purity
150 I.U./mg min.
Hazard Category
HYGROSCOPIC
RTECSNumber
MI0850000
TSCA
TSCA
RUO – Research Use Only
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