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Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns

Catalog No. p-4591250 Shop All Cytiva Products
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Ligand:
Product Type:

Designed for method optimization and parameter screening for capture of monoclonal antibodies. Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns come ready-to-use for convenience.

  • Ready-to-use columns for convenient process development
  • Rigid, highly cross-linked agarose matrix
  • Bed height of 10cm is designed to allow method optimization and parameter screening
  • Easily connected in series to achieve 20cm bed height
  • Small bed volume (4.7mL) gives fast result and minimal sample/buffer consumption
  • Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity

MabSelect

  • For capture of MAbs from large sample volumes
  • Prepacked with protein A-derived media
  • Compatible with high flow rates and high pressure when scaling up
MabSelect Xtra
  • Increased binding capacity enables purification of MAbs from high-level expression feedstock
  • Also optimized for Fc-fusion proteins
  • Very low, unspecific binding due to high ligand selectivity and matrix hydrophilicity
  • Prepacked with protein A-derived media
MabSelect SuRe (Superior Resistance) and MabSelect SuRe (Superior Resistance) LX
  • With novel, alkali-tolerant recombinant protein A ligand that provides greater stability and allows use of 0.1 to 0.5M sodium hydroxide for cleaning-in-place (CIP)
  • Enhanced protease resistance resulting in lower ligand leakage
  • High dynamic binding capacity

Specifications

Buffer

8M Urea, 6M Guanidine Hydrochloride, 2% Benzyl Alcohol or 20% Ethanol

Column Type

HiScreen MabSelect Prepacked Column

Description

Bed Dimensions: 7.7 × 100 mm

Includes

Stoppers at the inlet and outlet

Kit Size

1 x 4.7mL

Bed Support

Filter

Diameter (English) Inner

0.3 in.

Binding Capacity

≈30mg Human IgG

Diameter (Metric) Inner

0.77cm

Product Type

HiScreen MabSelect Prepacked Column

Height (English) Bed

3.93 in.

Height (Metric) Bed

100 mm

For Use With (Application)

Antibody affinity chromatography

Ligand

Recombinant Protein A (E.coli)

Ligand Coupling Method

Epoxy Activation

Material

Polypropylene

Particle Size

85μm

Max. Pressure

3 bar [0.3 MPa] (44 psi)

pH

3 to 10

Storage Requirements

2° to 8°C

Volume (Metric)

4.7 mL

Format

Column

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