Invitrogen™ Human D4 Dopamine Receptor (aa 93-112) Control Fragment Recombinant Protein

Description

Recombinant Protein

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Specifications

• Accession Number: P21917
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 1815
• Name: D4 Dopamine Receptor
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: AW125663; D(2C) dopamine receptor; D(4) dopamine receptor; D4DR; D4R; D4RA; Dopamine 4 receptor; Dopamine D4 receptor; dopamine receptor 4; dopamine receptor D4; DRD4; Drd-4; seven transmembrane helix receptor
• Gene Symbol: DRD4
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: YSEVQGGAWLLSPRLCDALM
• Expression System: E. coli
• Form: Liquid