Hyaluronic acid, bovine vitreous humor, Thermo Scientific Chemicals

Hyaluronic acid from bovine vitreous humor, CAS # 9004-61-9, is a naturally derived glycosaminoglycan that shows an angiogenic activity that promotes wound healing processes.

Hyaluronic acid is a naturally derived, non - immunogenic, non - adhesive glycosaminoglycan that plays a prominent role in various wound - healing processes, as it as it is naturally angiogenic when degraded to small fragments. Hyaluronic acid promotes early inflammation which is critical for initiating wound healing, but then moderates later stages of the process, allowing matrix stabilization and reduction of long term inflammation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Hyaluronic acid, derived from bovine vitreous humor, is a naturally derived, non-immunogenic, non-adhesive glycosaminoglycan that shows an angiogenic activity promoting wound-healing processes when degraded to small fragments

Application

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• It is considered a mucopolysaccharide composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine, which forms the core of complex proteoglycan aggregates found in the extracellular matrix

• It has been used to study the activation of the MAPK/ERK pathway following infection of macrophages with Leishmania amazonensis

Chemical Identifiers

CAS

9004-61-9

Molecular Formula

C28H44N2O23

Molecular Weight (g/mol)

776.651

MDL Number

MFCD00131348

InChI Key

KIUKXJAPPMFGSW-YXBJCWEESA-N

Synonym

hyaluronic acid, dsstox_cid_26750, dsstox_rid_81875, dsstox_gsid_46750, 4xi-alpha-d-xylo-hexopyranuronosyl-1->3-3xi-2-acetylamino-2-deoxy-beta-d-ribo-hexopyranosyl-1->4-5xi-beta-d-xylo-hexopyranuronosyl-1->3-2-acetylamino-2-deoxy-d-glucopyranose

PubChem CID

24728612

IUPAC Name

(2S,4S,5R,6S)-6-[(2S,3R,5S,6R)-3-acetamido-2-[(3S,4R,5R,6R)-6-[(3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid

SMILES

CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O

Color

White

Quantity

50 mg

Merck Index

14,4757

Solubility Information

Soluble in water.

Physical Form

Lyophilized Powder

Chemical Name or Material

Hyaluronic acid, bovine vitreous humor

EINECSNumber

232-678-0

TSCA

Yes

Recommended Storage

Keep cold

SDS

EINECSNumber

232-678-0

TSCA

Yes

Recommended Storage

Keep cold

SDS

RUO – Research Use Only