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AdipoGen Hyperforin DCHA

Chemical. CAS 238074-03-8. Formula C35H51O4 . C12H24N. MW 535.8 . 182.3. Isolated from St. Johns wort Hypericum perforatum. Key constituent of St. Johns wort. Shows properties of potential pharmacological interest, including antibacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses serotonin, norepinephrine, dopamine, GABA, glutamate. Activator of the pregnane X receptor PXR. Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 sirtuin 1 and SIRT2 sirtuin 2 inhibitor.
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