Iodoacetic acid, 97+%, Thermo Scientific Chemicals

Description

Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

Solubility
Soluble in water, alcohol and ethanol. Slightly soluble in ether and chloroform.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, bases and strong reducing agents.

Specifications

Chemical Identifiers

• CAS: 64-69-7
• Molecular Formula: C2H3IO2
• Molecular Weight (g/mol): 185.948
• MDL Number: MFCD00002685
• InChI Key: JDNTWHVOXJZDSN-UHFFFAOYSA-N
• Synonym: iodoacetic acid, acetic acid, iodo, iodoacetate, monoiodoacetic acid, monoiodoacetate, monoiodine acetate, iodoaceticacid, iodoethanoic acid, acetic acid, 2-iodo, kyselina jodoctova
• PubChem CID: 5240
• ChEBI: CHEBI:74571
• IUPAC Name: 2-iodoacetic acid
• SMILES: C(C(=O)O)I

• Melting Point: 79°C to 82°C
• Boiling Point: 208°C (decomposition)
• Odor: Pungent
• Quantity: 25 g
• UN Number: UN2923
• Beilstein: 1739079
• Sensitivity: Light sensitive
• Merck Index: 14,5025
• Solubility Information: Soluble in water,alcohol and ethanol. Slightly soluble in ether and chloroform.
• Formula Weight: 185.95
• Percent Purity: ≥97%
• Chemical Name or Material: Iodoacetic acid

Safety and Handling

Hazard Category	H301-H314
Hazard Statement	GHS H Statement H301-H314 Toxic if swallowed. Causes severe skin burns and eye damage.
Precautionary Statement	P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: I
EINECSNumber	200-590-1
RTECSNumber	AI3500000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only