Thermo Scientific Chemicals Ionomycin Calcium Salt, 99%

 

Supplier:  Thermo Scientific Chemicals J60628LB0

Catalog No. AAJ60628LB0

Description

Ionomycin calcium salt is used as a polyether antibiotic and apoptotic degeneration inducer. Ionomycin induces apoptotic degeneration of embryonic cortical neurons and cell cycle arrest at G1 phase. It is more effective than A23187 (sc-3591) and provides a useful tool for increasing intracellular Ca2+ concentration.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

• CAS: 56092-82-1
• Molecular Weight (g/mol): 747.08
• IUPAC Name: calcium (4R,6S,8S,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl-[2,2'-bioxolan]-5-yl]-4,6,8,12,14,18,20-heptamethyl-9,11-dioxodocos-16-en-10-idoate

• Molecular Formula: C41H70CaO9
• InChI Key: RULWQOBWZOQCOY-SQNLDGQHSA-M
• SMILES: [Ca++].C[C@H](CCC([O-])=O)C[C@H](C)C[C@H](C)C(=O)[CH-]C(=O)[C@H](C)C[C@H](C)C\C=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]1CC[C@](C)(O1)[C@@H](C)O

Specifications

• Quantity: 5 mg
• Content And Storage: -30°C to -10°C
• CAS: 56092-82-1
• Formula Weight: 747.08
• Solubility: Soluble in DMSO (10mg/ml). Also soluble in ethanol or methanol
• Form: Crystalline powder
• InChI Key: RULWQOBWZOQCOY-SQNLDGQHSA-M
• IUPAC Name: calcium (4R,6S,8S,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl-[2,2'-bioxolan]-5-yl]-4,6,8,12,14,18,20-heptamethyl-9,11-dioxodocos-16-en-10-idoate
• Assay: 99%

• Description: White to off-white
• For Use With (Application): Highly selective and potent calcium ionophore
• Molecular Formula: C41H70CaO9
• Sensitivity: Light Sensitive
• Product Type: Ionomycin Calcium Salt, 99%
• Beilstein: 1416163
• SMILES: [Ca++].C[C@H](CCC([O-])=O)C[C@H](C)C[C@H](C)C(=O)[CH-]C(=O)[C@H](C)C[C@H](C)C\C=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]1CC[C@](C)(O1)[C@@H](C)O
• Molecular Weight (g/mol): 747.08

Safety and Handling

Recommended Storage : Store at -20°C